89-7806-82 [取扱停止]Recombinant Mouse PKC delta/PRKCD Protein (His & GST Tag)(Active) 50ug PKSM040304
[Elabscience]特徴
- 背景:PRKCD, a novel member of the pkc gene family, maps to human chromosome 3.Protein kinase C (PKC) delta (PRKCD) is a member of the novel PKC subfamily that regulates gene expression in bovine trophoblast cells.Protein kinase Cdelta (PRKCD) initiates this process by phosphorylating FBXO25 and HAX-1, thereby spatially directing nuclear FBXO25 to mitochondrial HAX-1.PRKCD may suppress macroautophagy/autophagy, a cytoprotective mechanism, to promote kidney tubule cell death during cisplatin treatment. Interestingly, PRKCD may do so by phosphorylating AKT, which further phosphorylates MTOR to repress ULK1.
仕様
- サイズ:50ug
- 種由来:Mouse
- 発現宿主:Baculovirus-Insect Cells
- 純度:> 93 % as determined by SDS-PAGE
- エンドトキシン濃度:< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:P28867-1
- タグ種類:N-His-GST
- アミノ酸配列:Met 1-Ile 674
- 遺伝子構造:A DNA sequence encoding the mouse PRKCD isoform 1 (P28867-1) (Met 1-Ile 674) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 活性:Kinase activity untested
- 別名(遺伝子名):AI385711;D14Ertd420e;Pkcd;PKCdelta;PKC[d]
- 分子量:106 kDa
- 組成:Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.0
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-107036-Elabscience-PKSM040304.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
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89-7806-81
Recombinant Mouse PKC delta/PRKCD Protein (His & GST Tag)(Active) 20ug
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89-7806-82
Recombinant Mouse PKC delta/PRKCD Protein (His & GST Tag)(Active) 50ug
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