特徴
- 背景:Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:Q8IXJ9
- タグ種類:N-GST
- アミノ酸配列:Lys1477-Arg154
- 遺伝子構造:Recombinant Human ASXL1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.
- 別名(遺伝子名):Putative Polycomb group protein ASXL1; Additional sex combs-like protein 1; ASXL1; KIAA0978;
- 分子量:33.6 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229613-Elabscience-PKSH033781.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7805-84
Recombinant Human ASXL1 Protein (GST Tag) 10ug
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89-7805-85
Recombinant Human ASXL1 Protein (GST Tag) 50ug
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