特徴
- 背景：CD38; also called ADP-ribosyl cyclase; is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes; osteoclasts; and in cardiac; pancreatic; liver and kidney cells. Through its production of cyclic ADP-ribose; CD38 modulates calcium-mediated signal transduction in many types of cells; including neutrophils and pancreatic beta cells.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P28907
- タグ種類：C-mFc
- アミノ酸配列：Val43-Ile300
- 遺伝子構造：Recombinant Human CD38 is produced by our Mammalian expression system and the target gene encoding Val43-Ile300 is expressed with a mFc tag at the C-terminus.
- 別名（遺伝子名）：ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule;CD38
- 分子量：56.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris; 150mM NaCl; PH8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229609-Elabscience-PKSH033777.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7805-78
Recombinant Human CD38 Protein (mFc Tag) 10ug
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89-7805-79
Recombinant Human CD38 Protein (mFc Tag) 50ug
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