89-7805-50 ［取扱停止］Recombinant Human BCL2/Bcl-2 Protein (His Tag) 10ug PKSH033761
[Elabscience]
特徴
- 背景：Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability. Bcl-2 is an antiapoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types. BCL-2 is localized to the outer membrane of mitochondria,where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins. The pro-apoptotic proteins in the BCL-2 family, including Bax and Bak, normally act on the mitochondrial membrane to promote permeabilization and release of cytochrome C and ROS, that are important signals in the apotosis cascade. These pro-apoptotic proteins are in turn activated by BH3-only proteins, and are inhibited by the function of BCL-2 and its relative BCL-Xl.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P10415
- タグ種類：C-His
- アミノ酸配列：Met1-Asp211
- 遺伝子構造：Recombinant Human BCL2 is produced by our E.coli expression system and the target gene encoding Met1-Asp211 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Apoptosis regulator Bcl-2; BCL2; Apoptosis Regulator Bcl-2; B-cell Lymphoma 2;PPP1R50
- 分子量：24.1 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10%Glycerol, pH8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229594-Elabscience-PKSH033761.pdf
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89-7805-50
Recombinant Human BCL2/Bcl-2 Protein (His Tag) 10ug
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89-7805-51
Recombinant Human BCL2/Bcl-2 Protein (His Tag) 50ug
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