特徴
- 背景：Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues; with particularly high expression in the adult heart; testis; liver; skeletal muscle; fetal liver; and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2; and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P78560
- アミノ酸配列：Met1-Glu199
- 遺伝子構造：Recombinant Human CRADD is produced by our E.coli expression system and the target gene encoding Met1-Glu199 is expressed.
- 別名（遺伝子名）：Death Domain-Containing Protein CRADD; Caspase and RIP Adapter with Death Domain; RIP-Associated Protein with A Death Domain; CRADD; RAIDD
- 分子量：23 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229571-Elabscience-PKSH033738.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7805-05
Recombinant Human CRADD/RAIDD Protein 50ug
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89-7805-04
Recombinant Human CRADD/RAIDD Protein 10ug
|
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