89-7804-84 Recombinant Human CD226/DNAM-1 Protein (His Tag) 50ug PKSH033728
[Elabscience]特徴
- 背景:Human DNAX accessory molecule 1 (DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain (ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells; CD8+ T cells; and mast cells; dendritic cell maturation; megakaryocyte and activated platelet adhesion to vascular endothelial cells; and monocyte extravasation; it inhibits the forrmation of osteoclasts. Plateletendothelium; interactions mediated by DNAM-1; enable the metastasis of tumor cells to the lung.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:Q15762
- タグ種類:C-His
- アミノ酸配列:Glu19-Asn247
- 遺伝子構造:Recombinant Human CD226 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn247 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226; DNAM1
- 分子量:26.8 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS; pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229561-Elabscience-PKSH033728.pdf
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89-7804-83
Recombinant Human CD226/DNAM-1 Protein (His Tag) 10ug
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89-7804-84
Recombinant Human CD226/DNAM-1 Protein (His Tag) 50ug
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