89-7804-77 ［取扱停止］Recombinant Human CD40L/TNFSF5 Protein (E.coli)(Active) 10ug PKSH033725
[Elabscience]
特徴
- 背景：CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members; CD40LG exists as a trimer in membrane bound and soluble form; both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma; TNF-alpha; and IL2.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P29965
- アミノ酸配列：Met113-Leu261
- 遺伝子構造：Recombinant Human CD40L is produced by our E.coli expression system and the target gene encoding Met113-Leu261 is expressed.
- 活性：Immobilized Human CD40L at 5μg/ml(100 μl/well) can bind Human CD40-Fc(Cat: PKSH032216). The ED50 of Human CD40L is 68.55ug/ml.
- 別名（遺伝子名）：CD40 Ligand; CD40-L; T-Cell Antigen Gp39; TNF-Related Activation Protein; TRAP; Tumor Necrosis Factor Ligand Superfamily Member 5; CD154; CD40LG; CD40L; TNFSF5; TRAP;hCD40L;HIGM1;IGM;IMD3;T-BAM;TNFSF5;TRAP
- 分子量：16.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 200mM NaCl; 0.1mM EDTA; pH 7.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229558-Elabscience-PKSH033725.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7804-78
Recombinant Human CD40L/TNFSF5 Protein (E.coli)(Active) 50ug
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89-7804-77
Recombinant Human CD40L/TNFSF5 Protein (E.coli)(Active) 10ug
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