89-7804-75 Recombinant Human CD40/TNFRSF5 Protein (mFc Tag) 10ug PKSH033724
[Elabscience]特徴
- 背景:CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells; follicular dendritic cells; dendritic cells; activated monocytes; macrophages; endothelial cells; vascular smooth muscle cells; and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules; which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching; memory B cell development; and germinal center formation.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P25942
- タグ種類:C-mFc
- アミノ酸配列:Glu21-Arg193
- 遺伝子構造:Recombinant Human CD40 Receptor is produced by our Mammalian expression system and the target gene encoding Glu21-Arg193 is expressed with a mFc tag at the C-terminus.
- 別名(遺伝子名):Tumor Necrosis Factor Receptor Superfamily member 5; B-Cell Surface Antigen CD40; Bp50; CD40L Receptor; CDw40; CD40; TNFRSF5
- 分子量:45.7 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229557-Elabscience-PKSH033724.pdf
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89-7804-76
Recombinant Human CD40/TNFRSF5 Protein (mFc Tag) 50ug
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89-7804-75
Recombinant Human CD40/TNFRSF5 Protein (mFc Tag) 10ug
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