89-7804-29 Recombinant Human Decorin Protein (Baculovirus, His Tag) 10ug PKSH033701
[Elabscience]特徴
- 背景:Decorin is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). SLRP family members are characterized by N-terminal and C-terminal cysteine-rich regions which flank the central region containing 10-12 tandem leucine-rich repeats (LRR). The human Decorin cDNA encodes a 359 amino acid (aa) precursor that includes a 16 aa signal sequence and a 14 aa propeptide. Alternate splicing of human Decorin generates five isoforms with variable length deletions. Decorin is an N-glycosylated protein that also carries a variablysized hybrid chondroitin/dermatan sulfate chain at Ser34. Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors FGF2;GDF8/Myostatin; TGFβ;and WISP1. It also binds and activates EGF R; ErbB4; and IGFI-R. In vivo; Decorin promotes myoblast differentiation; supports angiogenesis; and inhibits tumor progression.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Baculovirus
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P07585
- タグ種類:C-His
- アミノ酸配列:Gly17-Lys359
- 遺伝子構造:Recombinant Human Decorin is produced by our Baculovirus expression system and the target gene encoding Gly17-Lys359 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Decorin; Bone proteoglycan II; PG-S2; PG40; DCN; SLRR1B
- 分子量:38.8 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS; pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229534-Elabscience-PKSH033701.pdf
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89-7804-29
Recombinant Human Decorin Protein (Baculovirus, His Tag) 10ug
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89-7804-30
Recombinant Human Decorin Protein (Baculovirus, His Tag) 50ug
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