89-7803-68 Recombinant Human SerpinE2/SERPINE2 Protein (His Tag) 10ug PKSH033671
[Elabscience]
特徴
- 背景：Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown that Serpin E2 is a novel target of ERK signaling involved in human colorectal tumorigenesis. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P07093-2
- タグ種類：C-His
- アミノ酸配列：Ser20-Pro397
- 遺伝子構造：Recombinant Human Serpin E2 is produced by our Mammalian expression system and the target gene encoding Ser20-Pro397 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serpin E2; SERPINE2; PI7; PN1
- 分子量：42.7 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229504-Elabscience-PKSH033671.pdf
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89-7803-69
Recombinant Human SerpinE2/SERPINE2 Protein (His Tag) 50ug
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89-7803-68
Recombinant Human SerpinE2/SERPINE2 Protein (His Tag) 10ug
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