特徴
- 背景：High mobility group protein B1 is a member of the HMGB family consisting of three members; HMGB1; HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein; HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile; it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte; T cell; dendritic cell activities in inflammatory responses.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P09429
- アミノ酸配列：Gly2-Phe89
- 遺伝子構造：Recombinant Human HMGB1 is produced by our E.coli expression system and the target gene encoding Gly2-Phe89 is expressed.
- 別名（遺伝子名）：High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1
- 分子量：10.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 50mMHepes;500mMNaCl;0.5mMDTT; pH7.9 .
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229487-Elabscience-PKSH033654.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7803-34
Recombinant Human HMGB1 Protein 10ug
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89-7803-35
Recombinant Human HMGB1 Protein 50ug
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