89-7802-27 Recombinant Human CD47/IAP Protein (His Tag)(Active) 10ug PKSH033600
[Elabscience]特徴
- 背景:CD47(Integrin-Associated Protein;IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages; neutrophils; and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin; and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution; and is reduced in expression on Rh erythrocytes.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:Q08722
- タグ種類:C-His
- アミノ酸配列:Gln19-Pro139
- 遺伝子構造:Recombinant Human CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a 6His tag at the C-terminus.
- 活性:Immobilized Human SIRPA-Fc(Cat: PKSH033061) at 10μg/ml(100 μl/well) can bind Human CD47-His. The ED50 of Human CD47-His is 4.18 ng/ml .
- 別名(遺伝子名):Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
- 分子量:14.76 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 10mM Tris-Citrate; 150mM NaCl; pH 8.0.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229433-Elabscience-PKSH033600.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7802-28
Recombinant Human CD47/IAP Protein (His Tag)(Active) 50ug
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89-7802-27
Recombinant Human CD47/IAP Protein (His Tag)(Active) 10ug
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