89-7802-20 Recombinant Human LAG3/CD223 Protein (His Tag)(Active) 50ug PKSH033596
[Elabscience]
特徴
- 背景：Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule; LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P18627
- タグ種類：C-His
- アミノ酸配列：Leu23-Leu450
- 遺伝子構造：Recombinant Human LAG3 Protein is produced by our Mammalian expression system and the target gene encoding Leu23-Leu450 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Human LAG-3-His at 5μg/ml(100 μl/well) can bind Human FGL1-mFc(Cat: PKSH033679). The ED50 of Human LAG-3-His is 29 ng/ml.
- 別名（遺伝子名）：Lymphocyte activation gene 3 protein;LAG3;LAG-3;Protein FDC;CD223;LAG-3
- 分子量：47.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS;2mMEDTA;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229429-Elabscience-PKSH033596.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7802-19
Recombinant Human LAG3/CD223 Protein (His Tag)(Active) 10ug
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89-7802-20
Recombinant Human LAG3/CD223 Protein (His Tag)(Active) 50ug
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