89-7802-12 Recombinant Human c-KIT/CD117 Protein (His Tag) 50ug PKSH033592
[Elabscience]
特徴
- 背景：C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing stimuli, and it is required for subsequent dendritic cell induction of Th2 and Th17 responses. SCF R protects vascular smooth muscle cells from apoptosis and assists in the recovery of cardiac function following myocardial infarction.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P10721
- タグ種類：C-His
- アミノ酸配列：Gln26-Thr520
- 遺伝子構造：Recombinant Human KIT is produced by our Mammalian expression system and the target gene encoding Gln26-Thr520 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117;PBT
- 分子量：56.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229425-Elabscience-PKSH033592.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7802-12
Recombinant Human c-KIT/CD117 Protein (His Tag) 50ug
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89-7802-11
Recombinant Human c-KIT/CD117 Protein (His Tag) 10ug
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