特徴
- 背景：MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P08254
- タグ種類：C-His
- アミノ酸配列：Tyr18-Cys477(Lys45Glu)
- 遺伝子構造：Recombinant Human MMP-3 is produced by our Mammalian expression system and the target gene encoding Tyr18-Cys477(Lys45Glu) is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Stromelysin-1; SL-1; Matrix metalloproteinase-3;Transin-1; MMP3; STMY1;CHDS6;MMP-3;SL-1;STMY;STR1
- 分子量：53.26 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229424-Elabscience-PKSH033591.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7802-09
Recombinant Human MMP-3 Protein (His Tag) 10ug
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89-7802-10
Recombinant Human MMP-3 Protein (His Tag) 50ug
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