特徴
- 背景：Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q92823-3
- タグ種類：C-Fc
- アミノ酸配列：Gln25-Asn600(Pro526Ala)
- 遺伝子構造：Recombinant Human NRCAM is produced by our Mammalian expression system and the target gene encoding Gln25-Asn600(Pro526Ala) is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Neuronal cell adhesion molecule; Nr-CAM; Neuronal surface protein Bravo; hBravo; gCAM-related cell adhesion molecule; Ng-CAM-related; KIAA0343; gCAM-related cell adhesion molecule
- 分子量：91.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229414-Elabscience-PKSH033581.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7801-88
Recombinant Human NRCAM Protein (Fc Tag) 10ug
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89-7801-89
Recombinant Human NRCAM Protein (Fc Tag) 50ug
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