89-7801-75 Recombinant Human Oncostatin M/OSM Protein (His Tag)(Active) 50ug PKSH033574
[Elabscience]
特徴
- 背景：Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological activities through specific cell surface receptors. The low affinity LIF receptor that shares the similarity of containing protein gp130 has now been identified to be a component of a high- affinity OSM receptor that will transduce OSM signals. OSM has also been shown to play a role in both pro and anti-inflammatory actions. OSM may also be involved in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P13725
- タグ種類：N-His
- アミノ酸配列：Ala26-Arg221
- 遺伝子構造：Recombinant Human Oncostatin M is produced by our E.coli expression system and the target gene encoding Ala26-Arg221 is expressed with a 6His tag at the N-terminus .
- 活性：Measured by the dose-dependent stimulation of TF-1 cells. The ED50 for this effect is 0.2-1ng/ml.
- 別名（遺伝子名）：Oncostatin-M; OSM
- 分子量：24.44 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229407-Elabscience-PKSH033574.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7801-75
Recombinant Human Oncostatin M/OSM Protein (His Tag)(Active) 50ug
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89-7801-74
Recombinant Human Oncostatin M/OSM Protein (His Tag)(Active) 10ug
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