89-7801-67 Recombinant Human Parathyroid Hormone/PTH Protein (His Tag) 50ug PKSH033570
[Elabscience]
特徴
- 背景：Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone; parathyroid hormone-related protein; binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones; parathyroid hormone is synthesized as a preprohormone. After intracellular processing; the mature hormone is packaged with in the Golgi into secretory vesicles; the secreted into blood by exocytosis. In renal epithelium; PTH promotes conversion of Vitamin D to its active form; lowers Ca++ excretion and increases phosphate excretion. PTH also increases hematopoietic stem cell proliferation and mobilization and induces arterial vasodilation by regulating Ca++ influx in PTH1R-expressing arterial smooth muscle.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P01270
- タグ種類：N-His
- アミノ酸配列：Ser32-Gln115
- 遺伝子構造：Recombinant Human Parathyroid Hormone is produced by our Mammalian expression system and the target gene encoding Ser32-Gln115 is expressed with a 8His tag at the N-terminus.
- 別名（遺伝子名）：Parathyroid Hormone; PTH; Parathormone; Parathyrin;PTH1
- 分子量：10.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229403-Elabscience-PKSH033570.pdf
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89-7801-66
Recombinant Human Parathyroid Hormone/PTH Protein (His Tag) 10ug
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89-7801-67
Recombinant Human Parathyroid Hormone/PTH Protein (His Tag) 50ug
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