89-7801-46 ［取扱停止］Recombinant Human PBEF/NAMPT Protein (His Tag) 10ug PKSH033560
[Elabscience]
特徴
- 背景：Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells; but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are due to its role as a Nampt which can induce angiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1. Extracellular PBEF has been shown to increase inflammatory cytokines; such as TNF-α; IL-1β; IL-16; and TGF-β1. PBEF also increases the production of IL-6; TNF-α; and IL-1β in CD14+ monocyctes; macrophages; and dendritic cells; enhances the effectiveness of T cells.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P43490
- タグ種類：N-His
- アミノ酸配列：Met1-His491
- 遺伝子構造：Recombinant Human PBEF is produced by our E.coli expression system and the target gene encoding Met1-His491 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Pre-B cell-enhancing factor; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Visfatin; NAMPT; PBEF; PBEF1
- 分子量：57 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM HEPES; 150mM NaCl; pH8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229393-Elabscience-PKSH033560.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7801-47
Recombinant Human PBEF/NAMPT Protein (His Tag) 50ug
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89-7801-46
Recombinant Human PBEF/NAMPT Protein (His Tag) 10ug
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