89-7801-30 Recombinant Human b-NGF/NGFB Protein (with pro peptide)(Active) 10ug PKSH033552
[Elabscience]特徴
- 背景:The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges; whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P01138
- アミノ酸配列:Glu19-Ala241
- 遺伝子構造:Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed.
- 活性:Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 32697 pg/mL.
- 別名(遺伝子名):Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB
- 分子量:25 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB; 250mM NaCl; pH 7.2.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229385-Elabscience-PKSH033552.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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89-7801-30
Recombinant Human b-NGF/NGFB Protein (with pro peptide)(Active) 10ug
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89-7801-31
Recombinant Human b-NGF/NGFB Protein (with pro peptide)(Active) 50ug
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