89-7800-32 Recombinant Human Thrombomodulin/CD141 Protein (His Tag) 50ug PKSH033501
[Elabscience]
特徴
- 背景：Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Human Thrombomodulin/THBD predicts a signal peptide and a mature chain that consists of following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Predominantly synthesized by vascular endothelial cells, THBD inhibits coagulation and fibrinolysis. THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis, stroke, arteriosclerosis, and cancer. For example, increased serum levels of THBD, due to protease cleavage, have been associated with smoking, cardiac surgery, atherosclerosis, liver cirrhosis, diabetes mellitus, cerebral and myocardial infarction, and multiple sclerosis.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P07204
- タグ種類：C-His
- アミノ酸配列：Ala19-Ser515
- 遺伝子構造：Recombinant Human Thrombomodulin is produced by our Mammalian expression system and the target gene encoding Ala19-Ser515 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Thrombomodulin; THBD; TM; Fetomodulin; CD141; THRM
- 分子量：52.9 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229334-Elabscience-PKSH033501.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7800-32
Recombinant Human Thrombomodulin/CD141 Protein (His Tag) 50ug
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89-7800-31
Recombinant Human Thrombomodulin/CD141 Protein (His Tag) 10ug
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