89-7799-99 Recombinant Human BCMA/TNFRSF17 Protein (mFc Tag) 50ug PKSH033485
[Elabscience]
特徴
- 背景：B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain; a 23 aa transmembrane domain; and a 113 aa intracellular domain. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF; it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF; members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface; BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development;function and regulation.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q02223
- タグ種類：C-mFc
- アミノ酸配列：Met1-Ala54
- 遺伝子構造：Recombinant Human BCMA is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a mFc tag at the C-terminus.
- 別名（遺伝子名）：Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma
- 分子量：32.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229318-Elabscience-PKSH033485.pdf
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
89-7799-98
Recombinant Human BCMA/TNFRSF17 Protein (mFc Tag) 10ug
|
|
|
89-7799-99
Recombinant Human BCMA/TNFRSF17 Protein (mFc Tag) 50ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|