89-7799-79 Recombinant Human VEGF165/VEGFA Protein (Active) 50ug PKSH033475
[Elabscience]
特徴
- 背景：Human Vascular endothelial growth factor (VEGF); also known as VEGF-A and vascular permeability factor (VPF); belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms; of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P15692-4
- アミノ酸配列：Ala27-Arg191
- 遺伝子構造：Recombinant Human VEGF165 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg191 is expressed.
- 活性：Immobilized Human VEGF165 at 10μg/ml (100 μl/well) can bind Human VEGFR2, The ED50 of Human VEGF165 is 433.6 ng/ml.
- 別名（遺伝子名）：MVCD1;VEGF;VEGF165;VPF;Vascular Endothelial Growth Factor Isoform 165
- 分子量：19.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229308-Elabscience-PKSH033475.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7799-79
Recombinant Human VEGF165/VEGFA Protein (Active) 50ug
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89-7799-78
Recombinant Human VEGF165/VEGFA Protein (Active) 10ug
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