特徴
- 背景：Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q14520
- タグ種類：C-6His
- アミノ酸配列：Met1-Gln279
- 遺伝子構造：Recombinant Human Hyaluronan-binding Protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Gln279 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Hyaluronan-binding protein 2; Factor VII-activating protease; Factor seven-activating protease; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding protein
- 分子量：36.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-231518-Elabscience-PKSH033464.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7799-67
Recombinant Human HABP2 Protein (His Tag) 50ug
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89-7799-66
Recombinant Human HABP2 Protein (His Tag) 10ug
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