89-7799-53 Recombinant Human Arginase-1/ARG1 Protein (His Tag)(Active) 50ug PKSH033453
[Elabscience]
特徴
- 背景：Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_000036.2
- タグ種類：C-6His
- アミノ酸配列：Met 1-Lys322
- 遺伝子構造：Recombinant Human Arginase-1 is produced by our Mammalian expression system and the target gene encoding Met1-Lys322 is expressed with a 6His tag at the C-terminus.
- 活性：Measured by the production of urea during the hydrolysis of arginine. The specific activity is 46411 pmol/min/ug.
- 別名（遺伝子名）：Arginase-1; Liver-type arginase; Type I arginase; ARG1
- 分子量：35.6 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mMNaCl, 20%Glycerol,1mMDTT,pH7.4.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139491-Elabscience-PKSH033453.pdf
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89-7799-53
Recombinant Human Arginase-1/ARG1 Protein (His Tag)(Active) 50ug
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89-7799-52
Recombinant Human Arginase-1/ARG1 Protein (His Tag)(Active) 10ug
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