特徴
- 背景:Complement factor D; also known as adipsin; is a member of the chymotrypsin family of serine proteases; which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3; which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes; including immunity and inflammation.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P00746
- タグ種類:C-10His
- アミノ酸配列:Ile26-Ala253
- 遺伝子構造:Recombinant Human Complement factor D is produced by our Mammalian expression system and the target gene encoding Ile26-Ala253 is expressed with a 10His tag at the C-terminus.
- 別名(遺伝子名):Complement factor D; CFD; Adipsin; C3 convertase activator; Properdin factor D; DF; PFD;ADIPSIN;ADN;DF;FACTOR D
- 分子量:25.8 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM Tris; 150mM NaCl; pH7.5.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-139480-Elabscience-PKSH033442.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7799-30
Recombinant Human Factor D Protein (His Tag) 10ug
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89-7799-31
Recombinant Human Factor D Protein (His Tag) 50ug
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