89-7799-28 Recombinant Human DR6/TNFRSF21 Protein (His Tag) 10ug PKSH033441
[Elabscience]特徴
- 背景:Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart; brain; placenta; pancreas; lymph node; thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition; DR6 binds with N-APP; which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF-α.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:NP_055267.1
- タグ種類:C-6His
- アミノ酸配列:Gln42-Leu350
- 遺伝子構造:Recombinant Human Death Receptor 6 is produced by our Mammalian expression system and the target gene encoding Gln42-Leu350 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Tumor Necrosis Factor Receptor Superfamily Member 21; Death Receptor 6; CD358; TNFRSF21; DR6
- 分子量:34.6 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-139479-Elabscience-PKSH033441.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7799-29
Recombinant Human DR6/TNFRSF21 Protein (His Tag) 50ug
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89-7799-28
Recombinant Human DR6/TNFRSF21 Protein (His Tag) 10ug
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