89-7799-20 Recombinant Human E-Cadherin/CDH1 Protein (His Tag) 10ug PKSH033437
[Elabscience]
特徴
- 背景：E-Cadherin is a classical member of the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats; a transmembrane region; and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric; breast; colorectal; thyroid; and ovarian cancers. Loss of function is thought to contribute to progression in cancer by increasing proliferation; invasion; and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells; and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. Also; E-Cadherin has a potent invasive suppressor role and it is a ligand for integrin alpha-E/beta-7.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P12830
- タグ種類：C-6His
- アミノ酸配列：Asp155-Ile707
- 遺伝子構造：Recombinant Human Cadherin-1/E-Cadherin/CDH1 is produced by our Mammalian expression system and the target gene encoding Asp155-Ile707 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Cadherin-1; CDH1;CAM 120/80;E-cadherin; CD324;CDHE;E-cad;E-Cadherin;ECAD;LCAM;UVO;Arc-1
- 分子量：61.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139475-Elabscience-PKSH033437.pdf
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89-7799-21
Recombinant Human E-Cadherin/CDH1 Protein (His Tag) 50ug
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89-7799-20
Recombinant Human E-Cadherin/CDH1 Protein (His Tag) 10ug
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