89-7798-77 Recombinant Human OX40/TNFRSF5 Protein (His Tag)(Active) 10ug PKSH033416
[Elabscience]
特徴
- 背景：OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_003318.1
- タグ種類：C-6His
- アミノ酸配列：Leu29-Ala216
- 遺伝子構造：Recombinant Human OX40L Receptor is produced by our Mammalian expression system and the target gene encoding Leu29-Ala216 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Human OX40L-His(Cat: PKSH032842) at 0.1μg/ml(100 μl/well) can bind Biotinylated Human OX40-His. The ED50 of Human OX40-His is 14.89 ug/ml.
- 別名（遺伝子名）：Tumor necrosis factor receptor superfamily member 4;TNFRSF4;OX40;CD134;Txgp1;ACT35;IMD16;TXGP1L
- 分子量：21.0 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139454-Elabscience-PKSH033416.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7798-78
Recombinant Human OX40/TNFRSF5 Protein (His Tag)(Active) 50ug
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89-7798-77
Recombinant Human OX40/TNFRSF5 Protein (His Tag)(Active) 10ug
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