89-7798-57 ［取扱停止］Recombinant Human CD80/B7-1 Protein (His Tag)(Active) 10ug PKSH033406
[Elabscience]
特徴
- 背景：Cluster of Differentiation 80; also called B7-1; is a member of cell surface immunoglobulin superfamily which plays key; yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_005182.1
- タグ種類：C-6His
- アミノ酸配列：Val35-Asn242
- 遺伝子構造：Recombinant Human Activation B7-1 antigen is produced by our Mammalian expression system and the target gene encoding Val35-Asn242 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Human CD28-Fc(Cat: PKSH032211) at 10μg/ml(100 μl/well) can bind Human B7-1 -His. The ED50 of Human B7-1 -His is 14.3 ug/mL
- 別名（遺伝子名）：CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80;B7-1;B7.1;CD28LG;LAB7
- 分子量：24.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139444-Elabscience-PKSH033406.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7798-58
Recombinant Human CD80/B7-1 Protein (His Tag)(Active) 50ug
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89-7798-57
Recombinant Human CD80/B7-1 Protein (His Tag)(Active) 10ug
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