89-7798-45 [取扱停止]Recombinant Human Urokinase/uPA Protein (His Tag) 10ug PKSH033400
[Elabscience]特徴
- 背景:Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:NP_002649.1
- タグ種類:C-6His
- アミノ酸配列:Ser21-Leu431
- 遺伝子構造:Recombinant Human Urokinase-Type Plasminogen Activator is produced by our Mammalian expression system and the target gene encoding Ser21-Leu431 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Urokinase-Type Plasminogen Activator; U-Plasminogen Activator; uPA;PLAU;ATF;BDPLT5;QPD;u-PA;UPA;URK
- 分子量:47.4 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 2mM CaCl, 10% Glycerol, pH 7.5.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-139438-Elabscience-PKSH033400.pdf
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89-7798-46
Recombinant Human Urokinase/uPA Protein (His Tag) 50ug
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89-7798-45
Recombinant Human Urokinase/uPA Protein (His Tag) 10ug
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