89-7798-35 Recombinant Human IL17RA Protein (Fc Tag)(Active) 10ug PKSH033395
[Elabscience]
特徴
- 背景：Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_055154.3
- タグ種類：C-Fc
- アミノ酸配列：Leu33-Trp320
- 遺伝子構造：Recombinant Human Interleukin-17 receptor A is produced by our Mammalian expression system and the target gene encoding Leu33-Trp320 is expressed with a Fc tag at the C-terminus.
- 活性：Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 20-100 ng/ml.
- 別名（遺伝子名）：CD127;CDW127;IL-17R;IL-17R-alpha;IL7RA;ILRA; IL-17RA; IL-17 R alpha; Interleukin-17 receptor A
- 分子量：60.6 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139433-Elabscience-PKSH033395.pdf
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89-7798-36
Recombinant Human IL17RA Protein (Fc Tag)(Active) 50ug
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89-7798-35
Recombinant Human IL17RA Protein (Fc Tag)(Active) 10ug
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