特徴
- 背景：Fibronectin Leucine Rich Transmembrane protein 2 (FLRT2) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1; FLRT2 and FLRT3; all contain 10 leucine-rich repeats (LRR); a type III fibronectin (FN) domain; followed by the transmembrane region; and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell cell association. FLRT2 is expressed in a subset of the sclerotome; adjacent to the region that forms the syndetome; suggesting its involvement in the FGF signalling pathway.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：O43155
- タグ種類：C-6His
- アミノ酸配列：Cys36-Ser539
- 遺伝子構造：Recombinant Human Fibronectin Leucine Rich Transmembrane Protein 2 is produced by our Mammalian expression system and the target gene encoding Cys36-Ser539 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Leucine-Rich Repeat Transmembrane Protein FLRT2; Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2; FLRT2; KIAA0405
- 分子量：57.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139410-Elabscience-PKSH033372.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7797-91
Recombinant Human FLRT2 Protein (His Tag) 50ug
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89-7797-90
Recombinant Human FLRT2 Protein (His Tag) 10ug
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