特徴
- 背景:The ST6GAL1 gene encodes β-Galactosamide α-2;6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2;6-sialylation of Galβ1;4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P15907
- タグ種類:C-6His
- アミノ酸配列:Lys27-Cys406
- 遺伝子構造:Recombinant Human beta-Galactoside alpha-2;6-Sialyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Lys27-Cys406 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Beta-Galactoside Alpha-2;6-Sialyltransferase 1; Alpha 2;6-ST 1; B-Cell Antigen CD75; CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2;6-Sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1; ST6GAL1; SIAT1
- 分子量:44.6 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 8.0.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-139400-Elabscience-PKSH033362.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7797-70
Recombinant Human ST6GAL1 Protein (His Tag) 10ug
|
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89-7797-71
Recombinant Human ST6GAL1 Protein (His Tag) 50ug
|
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