89-7797-65 Recombinant Human Jagged 1/JAG1 Protein (Fc Tag) 50ug PKSH033359
[Elabscience]
特徴
- 背景：Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development, JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1, which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_000205.1
- タグ種類：C-Fc
- アミノ酸配列：Gln34-Ser1046
- 遺伝子構造：Recombinant Human jagged-1 is produced by our Mammalian expression system and the target gene encoding Gln34-Ser1046 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Protein jagged-1 I; Jagged-1; JAGL1; HJ1; JAG1 and CD339;AGS;AHD;AWS;Jagged 1
- 分子量：138.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139397-Elabscience-PKSH033359.pdf
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89-7797-64
Recombinant Human Jagged 1/JAG1 Protein (Fc Tag) 10ug
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89-7797-65
Recombinant Human Jagged 1/JAG1 Protein (Fc Tag) 50ug
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