特徴
- 背景：CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney; placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5; 6; 7; 8; 10; or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling; T cell costimulation; B cell proliferation; and viral fusion with cell membranes.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P08195-1
- タグ種類：C-6His
- アミノ酸配列：Arg206-Ala630
- 遺伝子構造：Recombinant Human CD98 is produced by our Mammalian expression system and the target gene encoding Arg206-Ala630 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：4F2 Cell-Surface Antigen Heavy Chain; 4F2hc; 4F2 Heavy Chain Antigen; Lymphocyte Activation Antigen 4F2 Large Subunit; CD98; SLC3A2; MDU1;4F2;4F2HC;4T2HC;CD98HC;MDU1;NACAE
- 分子量：47.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; 5% Threhalose; pH 7.2.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139376-Elabscience-PKSH033338.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7797-22
Recombinant Human CD98 Protein (His Tag) 10ug
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89-7797-23
Recombinant Human CD98 Protein (His Tag) 50ug
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