特徴
- 背景：Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. It may repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_002373
- タグ種類：C-6His
- アミノ酸配列：Met 1-Ser151
- 遺伝子構造：Recombinant Human Myc-Associated Factor X is produced by our E.coli expression system and the target gene encoding Met1-Ser151 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Protein Max; Class D Basic Helix-Loop-Helix Protein 4; bHLHd4;; Myc-Associated Factor X; MAX; BHLHD4
- 分子量：18.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 50mM Imidazole, 250mM NaCl, pH 8.5.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139355-Elabscience-PKSH033317.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7796-80
Recombinant Human MAX Protein (His Tag) 50ug
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89-7796-79
Recombinant Human MAX Protein (His Tag) 10ug
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