89-7796-76 ［取扱停止］Recombinant Human PPM1A Protein (His Tag) 50ug PKSH033315
[Elabscience]
特徴
- 背景：Protein Phosphatase 1A (PPM1A) is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1A has a broad specificity. PPM1A negatively regulates the activities of MAP kinases and MAP kinase kinases. Also; it negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3; resulting in their dissociation from SMAD4; nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. In addition; PPM1A can dephosphorylate cyclin-dependent kinases; and thus may be involved in cell cycle control.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P35813-1
- タグ種類：C-6His
- アミノ酸配列：Gly2-Trp382
- 遺伝子構造：Recombinant Human Protein Phosphatase 1A is produced by our E.coli expression system and the target gene encoding Gly2-Trp382 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Protein Phosphatase 1A; Protein Phosphatase 2C Isoform Alpha; PP2C-Alpha; Protein Phosphatase IA; PPM1A; PPPM1A;PP2C-ALPHA;PP2CA;PP2Calpha
- 分子量：43.5 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139353-Elabscience-PKSH033315.pdf
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89-7796-76
Recombinant Human PPM1A Protein (His Tag) 50ug
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89-7796-75
Recombinant Human PPM1A Protein (His Tag) 10ug
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