89-7796-10 Recombinant Human CSF2RA/GM-CSFR Protein (His Tag)(Active) 50ug PKSH033281
[Elabscience]
特徴
- 背景：Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P15509
- タグ種類：C-6His
- アミノ酸配列：Glu23-Gly320
- 遺伝子構造：Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit alhpa is produced by our Mammalian expression system and the target gene encoding Glu23-Gly320 is expressed with a 6His tag at the C-terminus.
- 活性：Measured by its ability to inhibit GM-CSF-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.5-2 μg/ml.
- 別名（遺伝子名）：Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha; GM-CSF-R-Alpha; GMCSFR-Alpha; GMR-Alpha; CDw116; CD116; CSF2RA; CSF2R; CSF2RY
- 分子量：35.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139320-Elabscience-PKSH033281.pdf
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89-7796-09
Recombinant Human CSF2RA/GM-CSFR Protein (His Tag)(Active) 10ug
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89-7796-10
Recombinant Human CSF2RA/GM-CSFR Protein (His Tag)(Active) 50ug
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