特徴
- 背景：b-Defensin 1 (DEFB1) is a member of the b-defensin family, which is highly expressed by epithelial cells. b-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. b-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. b-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in b-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. b-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, b-defensin 1 is associated with induction profiles in gingival keratinocytes.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P60022
- アミノ酸配列：Gly22-Lys68
- 遺伝子構造：Recombinant Human beta-Defensin 1 is produced by our E.coli expression system and the target gene encoding Gly22-Lys68 is expressed.
- 別名（遺伝子名）：Beta-Defensin 1; BD-1; hBD-1; Defensin Beta 1; DEFB1; BD1; HBD1
- 分子量：5.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 130mM NaCl, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106925-Elabscience-PKSH033264.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7795-74
Recombinant Human b-Defensin 1/DEFB1 Protein 10ug
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89-7795-75
Recombinant Human b-Defensin 1/DEFB1 Protein 50ug
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