特徴
- 背景：Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP participates in the formation of the transitional endoplasmic reticulum (tER) and regulates E3 ubiquitin-protein ligase activity of RNF19A.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P55072
- タグ種類：C-6His
- アミノ酸配列：Ala2-Asn589
- 遺伝子構造：Recombinant Human Valosin-Containing Protein is produced by our E.coli expression system and the target gene encoding Ala2-Asn589 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Transitional Endoplasmic Reticulum ATPase; TER ATPase; 15S Mg(2+)-ATPase p97 Subunit; Valosin-Containing Protein; VCP
- 分子量：66.4 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 50mM TrisHCl, pH8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106871-Elabscience-PKSH033203.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7794-67
Recombinant Human VCP Protein (His Tag) 10ug
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89-7794-68
Recombinant Human VCP Protein (His Tag) 50ug
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