89-7794-35 Recombinant Human HIP2/UBE2K Protein (His Tag, SUMO Tag) 10ug PKSH033186
[Elabscience]
特徴
- 背景：Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain; with highest levels found in cortex and striatum; and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins; such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition; UBE2K is involved in Alzheimer's disease; Huntington's disease and antigen processing through its interaction with huntingtin; and MHC-heavy chain proteins.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P61086
- タグ種類：N-6His
- アミノ酸配列：Met 1-Asn200
- 遺伝子構造：Recombinant Human Ubiquitin-Conjugating Enzyme E2 K is produced by our E.coli expression system and the target gene encoding Met1-Asn200 is expressed with a 6His; SUMO tag at the N-terminus.
- 別名（遺伝子名）：Ubiquitin-Conjugating Enzyme E2 K; Huntingtin-Interacting Protein 2; HIP-2; Ubiquitin Carrier Protein; Ubiquitin-Conjugating Enzyme E2-25 kDa; Ubiquitin-Conjugating Enzyme E2(25K); Ubiquitin-Conjugating Enzyme E2-25K; Ubiquitin-Protein Ligase; UBE2K; HIP2; LIG
- 分子量：34.5 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106855-Elabscience-PKSH033186.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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89-7794-36
Recombinant Human HIP2/UBE2K Protein (His Tag, SUMO Tag) 50ug
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89-7794-35
Recombinant Human HIP2/UBE2K Protein (His Tag, SUMO Tag) 10ug
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