89-7793-61 Recombinant Human TREML1/TLT-1 Protein (Fc Tag) 50ug PKSH033145
[Elabscience]
特徴
- 背景：Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide; a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain; and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q86YW5
- タグ種類：C-Fc
- アミノ酸配列：Gln16-Pro162
- 遺伝子構造：Recombinant Human Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Gln16-Pro162 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Trem-Like Transcript 1 Protein; TLT-1; Triggering Receptor Expressed on Myeloid Cells-Like Protein 1; TREML1; TLT1
- 分子量：42.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106818-Elabscience-PKSH033145.pdf
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89-7793-61
Recombinant Human TREML1/TLT-1 Protein (Fc Tag) 50ug
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89-7793-60
Recombinant Human TREML1/TLT-1 Protein (Fc Tag) 10ug
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