89-7791-72 Recombinant Human SerpinF1/PEDF Protein (His Tag) 10ug PKSH033042
[Elabscience]
特徴
- 背景：Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. Serpin F1 is a new promising approach for the treatment of osteosarcoma and has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P36955
- タグ種類：C-6His
- アミノ酸配列：Gln20-Pro418
- 遺伝子構造：Recombinant Human Serine Protease Inhibitor-clade F1 is produced by our Mammalian expression system and the target gene encoding Gln20-Pro418 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 Protein; EPC-1; Serpin F1; SERPINF1; PEDF;OI12;OI6;PEDF;PIG35
- 分子量：45.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106725-Elabscience-PKSH033042.pdf
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89-7791-73
Recombinant Human SerpinF1/PEDF Protein (His Tag) 50ug
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89-7791-72
Recombinant Human SerpinF1/PEDF Protein (His Tag) 10ug
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