特徴
- 背景：Pyruvate Kinase Isozymes R/L (PKLR) belongs to the pyruvate kinase family, There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver; R is found in red cells; M1 is the main form in muscle, heart and brain; M2 is found in early fetal tissues. PKLR exists as a homotetramer and catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in PKLR are also the cause of pyruvate kinase deficiency of red cells, which is a frequent cause of hereditary non-spherocytic hemolytic anemia.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P30613
- タグ種類：C-6His
- アミノ酸配列：Met 1-Ser574
- 遺伝子構造：Recombinant Human Pyruvate Kinase, Liver And RBC is produced by our Mammalian expression system and the target gene encoding Met1-Ser574 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Pyruvate Kinase Isozymes R/L; Pyruvate Kinase 1; R-Type/L-Type Pyruvate Kinase; Red Cell/Liver Pyruvate Kinase; PKLR; PK1; PKL
- 分子量：62.9 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT 0.2M NaCl, 10% glycerol, pH 8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106673-Elabscience-PKSH032984.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7790-69
Recombinant Human PKLR Protein (His Tag) 10ug
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89-7790-70
Recombinant Human PKLR Protein (His Tag) 50ug
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