89-7789-88 Recombinant Human Pro-Neuregulin-1/NRG1-‑b1 Protein (aa 2-246) 10ug PKSH032939
[Elabscience]
特徴
- 背景：Pro-neuregulin-1;Neuregulin-1 beta 1（NRG1） is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors; resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial; glial; neuronal; and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q02297-6
- アミノ酸配列：Ser2-Lys246
- 遺伝子構造：Recombinant Human Neuregulin-1 beta is produced by our E.coli expression system and the target gene encoding Ser2-Lys246 is expressed.
- 別名（遺伝子名）：Pro-neuregulin-1;Neuregulin-1 beta 1;NRG1-beta 1;HRG1-beta 1; EGF;NRG1; GGF; HGL; HRGA; NDF; SMDF;
- 分子量：26.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106633-Elabscience-PKSH032939.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7789-89
Recombinant Human Pro-Neuregulin-1/NRG1-‑b1 Protein (aa 2-246) 50ug
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89-7789-88
Recombinant Human Pro-Neuregulin-1/NRG1-‑b1 Protein (aa 2-246) 10ug
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