89-7789-77 Recombinant Human Prolactin/PRL Protein (His Tag) 50ug PKSH032930
[Elabscience]
特徴
- 背景：Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation; but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion; while glycosylated prolactin is reported to be constitutively secreted; have lower biological potency; and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals; where secretion is under tonic inhibition by hypothalamic dopamine. In humans; prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy; but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity; peripherally produced prolactin plays roles in breast and prostate cancer development; regulation of reproductive function; and immunoregulation.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P01236
- タグ種類：C-6His
- アミノ酸配列：Leu29-Cys227
- 遺伝子構造：Recombinant Human Prolactin is produced by our Mammalian expression system and the target gene encoding Leu29-Cys227 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Prolactin; PRL
- 分子量：23.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106627-Elabscience-PKSH032930.pdf
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89-7789-76
Recombinant Human Prolactin/PRL Protein (His Tag) 10ug
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89-7789-77
Recombinant Human Prolactin/PRL Protein (His Tag) 50ug
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