特徴
- 背景:Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:Q00887
- タグ種類:C-6His
- アミノ酸配列:Glu35-Ser426
- 遺伝子構造:Recombinant Human Pregnancy-specific beta-1-glycoprotein 9 is produced by our Mammalian expression system and the target gene encoding Glu35-Ser426 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Pregnancy-specific beta-1-glycoprotein 9; PS-beta-G-9; PSBG-9; Pregnancy-specific glycoprotein 9; PS34; Pregnancy-specific beta-1 glycoprotein B; PS-beta-B; Pregnancy-specific beta-1-glycoprotein 11; PS-beta-G-11; PSBG-11; Pregnancy-specific glycoprotein 11; Pregnancy-specific glycoprotein 7; PSG7; PSG11
- 分子量:45.6 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.5.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106624-Elabscience-PKSH032927.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7789-71
Recombinant Human PSG9/PSBG9 Protein (His Tag) 50ug
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89-7789-70
Recombinant Human PSG9/PSBG9 Protein (His Tag) 10ug
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