89-7788-73 Recombinant Human FKBP3/FKBP25 Protein (His Tag) 10ug PKSH032876
[Elabscience]
特徴
- 背景：FKBP25 contains 1 PPIase FKBP-type domain; belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin; as well as histone deacetylases; the transcription factor YY1; casein kinase II; and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q00688
- タグ種類：N-6His
- アミノ酸配列：Met 1-Asp224
- 遺伝子構造：Recombinant Human 25 kDa FK506-binding protein is produced by our E.coli expression system and the target gene encoding Met1-Asp224 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Peptidyl-prolyl cis-trans isomerase FKBP3;PPIase FKBP3;25 kDa FK506-binding protein;25 kDa FKBP;FKBP-25;FK506-binding protein 3;FKBP-3;Immunophilin FKBP25;Rapamycin-selective 25 kDa immunophilin;Rotamase;FKBP25
- 分子量：27.3 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl;1mM DTT;10% glycerol .
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106575-Elabscience-PKSH032876.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7788-73
Recombinant Human FKBP3/FKBP25 Protein (His Tag) 10ug
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89-7788-74
Recombinant Human FKBP3/FKBP25 Protein (His Tag) 50ug
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