89-7788-34 [取扱停止]Recombinant Human PAPS Synthase 1/PAPSS1 Protein (His Tag) 50ug PKSH032852
[Elabscience]特徴
- 背景:PAPSS1 is a bifunctional enzyme with both ATP sulfurylase and APS kinase activity. In the N-terminal section; it belongs to the APS kinase family; while the C-terminal section belongs to the sulfate adenylyltransferase family. PAPSS1 can be inhibited by chlorate; and is expressed in many tissues; such as high endothelial venules (HEV) cells and in cartilage. PAPSS1 mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS); and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate. In mammals; PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. PAPSS1 also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:O43252
- タグ種類:C-6His
- アミノ酸配列:Met 1-Ala624
- 遺伝子構造:Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Ala624(O43252) is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1;PAPS synthase 1;PAPSS 1;Sulfurylase kinase 1;SK 1;ATPSK1; PAPSS
- 分子量:71.9 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM Tris;100mM NaCl;20% glycerol;pH 8.0.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106554-Elabscience-PKSH032852.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7788-33
Recombinant Human PAPS Synthase 1/PAPSS1 Protein (His Tag) 10ug
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89-7788-34
Recombinant Human PAPS Synthase 1/PAPSS1 Protein (His Tag) 50ug
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